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European Journal of Gynaecological Oncology  2019, Vol. 40 Issue (1): 28-35    DOI: 10.12892/ejgo4181.2019
Original Research Previous articles | Next articles
Surgical management of recurrent gynecological cancer: Complete resection is the key to longer survival
S. Soeda1, *(), T. Watanabe1, S. Nomura1, M. Kojima1, S. Furukawa5, H. Endo3, Z. Saze3, T. Ozeki6, H. Nishiyama7, A. Kenjo3, T. Takahashi2, H. Yamada4, K. Fujimori1
1Departments of Obstetrics and Gynecology, Fukushima Medical University School of Medicine, Fukushima City, Fukushima, Japan
2Departments of Fukushima Medical Center for Children and Women, Fukushima Medical University School of Medicine, Fukushima City, Fukushima, Japan
3Departments of Surgery, Fukushima Medical University School of Medicine, Fukushima City, Fukushima, Japan
4Department of Gynecology, Miyagi Cancer Center, Medeshima-Shiode, Natori, Miyagi, Japan
5Department of Obstetrics and Gynecology, Shirakawa Kosei General Hospital, Toyochi, Shirakawa City, Fukushima, Japan
6Department of Obstetrics and Gynecology, Takeda General Hospital, Aizu, Wakamatsu City, Fukushima, Japan
7Department of Obstetrics and Gynecology, Iwaki Kyoritsu General Hospital, Uchigo, Mimaya-machi, Iwaki, Fukushima, Japan
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Abstract  

Purpose of investigation: This study was conducted to elucidate the efficacy and feasibility of surgical management of recurrent gynecological (cervical, endometrial, and ovarian) cancers. Materials and Methods: Patients undergoing surgical management for recurrent gynecological cancers at Fukushima Medical University between January 2001 and December 2012 were evaluated. Progression-free survival (PFS) and overall survival (OS) were each estimated using the Kaplan-Meier method and compared with the log-rank test. Results: Fifty patients underwent surgery for recurrent gynecological cancers (13 cervical, 18 endometrial, and 19 ovarian). On univariate analysis, complete surgery was a significant prognostic factor in all cancer types. On multivariate analysis, there were significant differences in complete surgery and the number of recurrent tumors for endometrial cancer. Conclusion: These results suggest that, in a select group of patients, especially in recurrent endometrial cancer, surgical management improves survival of recurrent gynecologic cancer patients, and it is valuable therapeutic option.

Key words:  Recurrent gynecological cancer      Surgical management      Complete surgery     
Published:  10 February 2019     
*Corresponding Author(s):  S. SOEDA     E-mail:  s-soeda@fmu.ac.jp

Cite this article: 

S. Soeda, T. Watanabe, S. Nomura, M. Kojima, S. Furukawa, H. Endo, Z. Saze, T. Ozeki, H. Nishiyama, A. Kenjo, T. Takahashi, H. Yamada, K. Fujimori. Surgical management of recurrent gynecological cancer: Complete resection is the key to longer survival. European Journal of Gynaecological Oncology, 2019, 40(1): 28-35.

URL: 

https://ejgo.imrpress.com/EN/10.12892/ejgo4181.2019     OR     https://ejgo.imrpress.com/EN/Y2019/V40/I1/28

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