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European Journal of Gynaecological Oncology  2019, Vol. 40 Issue (2): 290-294    DOI: 10.12892/ejgo4343.2019
Original Research Previous articles | Next articles
The effect of different cervical transformation zone types on the colposcopic diagnosis of cervical intraepithelial neoplasia
Aiping Fan1, Chen Wang1, Liqin Zhang1, Ye Yan1, Yingmei Wang1, Cha Han1, *(), Fengxia Xue1
1 Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China
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Abstract  
Purpose: To analyze the effects of cervical transformation zone (TZ) on the colposcopic diagnosis of cervical intraepithelial neoplasia (CIN). Materials and Methods: The authors retrospectively evaluated 482 patients who underwent conizaion between September 2012 and September 2016. The cytology, colposcopic impressions and histological diagnoses from biopsy and cone specimens were compared. Results: An agreement of 88.1% was observed between high-grade cytology and final histological diagnoses among the three TZ types. Significant differences between the colposcopic impressions and final histological diagnoses were observed for TZ types 1 and 2 vs. type 3. The overall agreement was 89.1% regarding the histology findings on colposcopically directed biopsy (CDB) and cone specimens, which correlated significantly with TZ (p = 0.004) and the number of cervical biopsies (p = 0.032). The agreement between histology results on endocervical curettage (ECC) and the final histology results was 28.24% in the patients with TZ type 3. Conclusions: Cervical TZ types variably influence colposcopically diagnostic accuracy for CIN, and TZ type 3 was associated with the lowest accuracy.
Key words:  Cervical intraepithelial neoplasia      Colposcopically directed biopsy      Colposcopy      Squamous intraepithelial lesions of the cervix      Transformation zone     
Published:  10 April 2019     
*Corresponding Author(s):  CHA HAN     E-mail:  2608750667@qq.com

Cite this article: 

Aiping Fan, Chen Wang, Liqin Zhang, Ye Yan, Yingmei Wang, Cha Han, Fengxia Xue. The effect of different cervical transformation zone types on the colposcopic diagnosis of cervical intraepithelial neoplasia. European Journal of Gynaecological Oncology, 2019, 40(2): 290-294.

URL: 

https://ejgo.imrpress.com/EN/10.12892/ejgo4343.2019     OR     https://ejgo.imrpress.com/EN/Y2019/V40/I2/290

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