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European Journal of Gynaecological Oncology  2019, Vol. 40 Issue (2): 232-235    DOI: 10.12892/ejgo4346.2019
Original Research Previous articles | Next articles
Oncology cytology and HPV DNA testing in women with cervical ectopy
S.M.S. Fernandes1, *(), J.C.L. Ribalta1, N.M.G. Speck1, Y. Yamamura2
1 Department of Gynecology, Federal University of São Paulo, São Paulo, Brazil
2 Department of Orthopedics and Traumatology-Gynecological Acupuncture, Federal University of São Paulo, São Paulo, Brazil
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Objective: To analyse women with ectopy, conventional Pap smear (CPS) and liquid-based cytology (LBC), high-risk HPV (HR-HPV) and its relationship to ectopic size. Materials and Methods: The authors selected 51 women with ectopy, without therapy, negative CPS, and no HPV-induced effect. The authors performed colposcopy, LBC, and HPV testing. They performed computerized planimetry to calculate the percentage of the ectopic area (PEA). The data were analyzed statistically. Results: The mean age was 25.6 years. LBC confirmed CPS predominating metaplastic and/or glandular epithelia, negative deviation to BV, and reactive/inflammatory conclusion. The authors detected atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intraepithelial lesions (LSIL) in 17.6% in LBC. HR-HPV was positive in 33% (p = 0.320), with a mean age of 22.8 years and with predominance of HPV other types (OT) in 25.5%. The mean PEA in HPV positive patients was 34.57% (p = 0.664). Conclusion: LBC confirmed the CPS. HPV OT predominated in the age group younger than 25 years. There was no relationship between HR-HPV and ectopic size.
Key words:  Ectopy      Conventional Pap smear      Liquid- based cytology      HPV-HR     
Published:  10 April 2019     
*Corresponding Author(s):  S.M. SILVA FERNANDES     E-mail:

Cite this article: 

S.M.S. Fernandes, J.C.L. Ribalta, N.M.G. Speck, Y. Yamamura. Oncology cytology and HPV DNA testing in women with cervical ectopy. European Journal of Gynaecological Oncology, 2019, 40(2): 232-235.

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