Please wait a minute...
European Journal of Gynaecological Oncology  2018, Vol. 39 Issue (6): 958-962    DOI: 10.12892/ejgo4391.2018
Original Research Previous articles | Next articles
"See and treat" LEEP biopsy for cervical intraepithelial neoplasia grade 2/3
A. Abe1, *(), M. Nishimura1, M. Irahara1
1 Department of Obstetrics and Gynecology, Tokushima University Hospital, Tokushima, Japan
Download:  PDF(228KB)  ( 73 )
Export:  BibTeX | EndNote (RIS)      
Abstract  
Purpose of investigation: To evaluate the safety and efficacy of loop electrosurgical excision procedure (LEEP) biopsy using a “seeand- treat” strategy, and compare outcomes after “LEEP biopsy, inpatient LEEP and ablation, and inpatient conization with cervical intraepithelial neoplasia (CIN) grade 2/3. Materials and Methods: The authors performed a retrospective study including 300 women with CIN2/3 who were followed up ≥ 6 months following outpatient LEEP/inpatient LEEP and ablation/inpatient conization. Recurrence, additional treatment for recurrence, pregnancy, and term delivery following treatment were evaluated. Results: During the median follow-up duration of 22 months, recurrences were significantly more common following LEEP biopsy (39%) compared to LEEP and ablation (13%) and conization (16%) and were managed by repeat LEEP. Pregnancy and full-term delivery rates following LEEP biopsy were significantly higher. Conclusion: “See-and-treat” LEEP biopsy was safely performed in the outpatient department. Pregnancy rates and full-term deliveries following LEEP biopsy appear favorable.
Key words:  Cervical intraepithelial neoplasia      Colposcopy      Electrosurgery      Papanicolaou test      Recurrence      Uterine cervical neoplasms     
Published:  10 December 2018     
*Corresponding Author(s):  AKIKO ABE     E-mail:  akiko06090111@yahoo.co.jp

Cite this article: 

A. Abe, M. Nishimura, M. Irahara. "See and treat" LEEP biopsy for cervical intraepithelial neoplasia grade 2/3. European Journal of Gynaecological Oncology, 2018, 39(6): 958-962.

URL: 

https://ejgo.imrpress.com/EN/10.12892/ejgo4391.2018     OR     https://ejgo.imrpress.com/EN/Y2018/V39/I6/958

[1] Mario Preti, Niccolò Gallio, Federica Bevilacqua, Giorgia Pasquero, Leonardo Micheletti, Chiara Benedetto. Cervical cone dimension and linear CIN extension trend: 28 years' experience of a tertiary center[J]. European Journal of Gynaecological Oncology, 2021, 42(5): 865-870.
[2] Luibov.I. Korolenkova, Ivan.S. Stilidi, Inna.N. Lazareva. Diagnostic value of colposcopy for cervical intraepithelial neoplasia 2–3/carcinoma in situ and microinvasive cervical cancer[J]. European Journal of Gynaecological Oncology, 2021, 42(5): 909-916.
[3] Xiaofang Yang, Lejun Chen, Dahai Yu, Wei Song, Jun Ma. Comparison between curative concurrent chemoradiotherapy followed by adjuvant chemotherapy and curative concurrent chemoradiotherapy alone in patients with locally advanced cervical carcinoma: a meta-analysis[J]. European Journal of Gynaecological Oncology, 2021, 42(5): 1029-1038.
[4] Paolo Giorgi Rossi, Anna Iossa, Carmen Beatriz Visioli, Francesco Venturelli, Paola Garutti, on behalf of the GISCi working group on follow up after treatment. Development of evidence-based guidelines for follow up of women treated for cervical intraepithelial neoplasia grade 2 or 3 (CIN2/3) in Italian screening programmes[J]. European Journal of Gynaecological Oncology, 2021, 42(5): 1079-1092.
[5] Raffaella Fabbri, Rossella Vicenti, Roberto Paradisi, Maria Macciocca, Valentina Magnani1, Lucia DE Meis, Stefania Rossi, Massimo Eraldo Abate, Stefania Benini, Renato Seracchioli. Ovarian tissue cryopreservation after chemotherapy and successful pregnancy after autograft and additional chemotherapy[J]. European Journal of Gynaecological Oncology, 2021, 42(5): 1095-1098.
[6] Ugo Indraccolo, Erica Santi, Piergiorgio Iannone, Chiara Borghi, Pantaleo Greco. Number of colposcopic cervical biopsies and diagnosis of cervical intraepithelial neoplasia: a prospective study[J]. European Journal of Gynaecological Oncology, 2021, 42(4): 649-654.
[7] Maria Szymankiewicz, Sebastian Szubert. Microbiological characteristics of early and late infectious complications following total pelvic exenteration due to cervical cancer recurrence—the significance of infections in long-term outcomes[J]. European Journal of Gynaecological Oncology, 2021, 42(4): 742-751.
[8] Qihui Feng, Qingli Li, Keyong Bao, Yue Wang, Ping Song, Peng Zuo, Mingzhu Li, Chao Zhao, Na Wang,Jingran Li, Rutie Yin, Lihui Wei. Analysis and comparison of the prevalence and genotype distribution of human papillomavirus in two different areas of China: a cross-sectional study[J]. European Journal of Gynaecological Oncology, 2021, 42(4): 795-801.
[9] Fang Liu, Yufang Zhang, Xinyi Xia, Jin Han, Danhong Hu. Diagnostic value of different colposcopy evaluation methods for high-grade squamous intraepithelial lesions and cervical cancer[J]. European Journal of Gynaecological Oncology, 2021, 42(3): 463-469.
[10] Kota Okamoto, Yoichi Aoki, Eiji Kondo, Yusuke Shimizu, Ai Ikki, Yuji Tanaka, Atsushi Fusegi, Makoto Nakabayashi, Makiko Omi, Tomoko Kurita, Terumi Tanigawa, Sachiho Netsu, Mayu Yunokawa, Hidetaka Nomura, Maki Matoda, Sanshiro Okamoto, Kohei Omatsu, Tomoaki Ikeda, Hiroyuki Kanao. Laparoscopic total vaginectomy for isolated vaginal recurrence of cervical cancer or high-grade squamous intraepithelial lesion after hysterectomy: a retrospective, single-centre cohort study[J]. European Journal of Gynaecological Oncology, 2021, 42(3): 494-498.
[11] Hacı Oztürk Şahin, Alpay Yilmaz, Mehmet Bayrak, Eren Pek, Kemal Özerkan, Hakan Ozan. Recurrence of borderline ovarian tumors: clinical and pathological risk factors[J]. European Journal of Gynaecological Oncology, 2021, 42(3): 580-586.
[12] Imari Deura, Yuko Nagasawa, Ryo Kanamori, Eriko Shiraishi, Yuki Horage, Shiho Kuji, Tatsuru Ohara, Nao Suzuki. Endometrial cancer with tubal metastasis detected during laparoscopic surgery in a patient undergoing fertility-sparing treatment with medroxyprogesterone acetate: a case report and review of the literature[J]. European Journal of Gynaecological Oncology, 2021, 42(3): 598-604.
[13] Gerritje W.J. van Rijn, Celine S. Bhugwandass, Saskia Houterman, Erik A. Boss, Anna A.M. van der Wurff, Ruud L.M. Bekkers, Jurgen M.J. Piek. Bilateral salpingo-oophorectomy in patients with uterine sarcoma: a multi-centre retrospective analysis[J]. European Journal of Gynaecological Oncology, 2021, 42(2): 286-292.
[14] Wen-Wen Xu, Jun Tian, Yi-Miao Zhu, Qing-Ling Ren. Clinical observation and mechanism of the elimination of HPV16/18/58 subtype infection and the reversal of grade I cervical intraepithelial neoplasia in Han Chinese women treated with modified Ermiao granules[J]. European Journal of Gynaecological Oncology, 2021, 42(2): 293-299.
[15] Rikiya Sano, Yoshiaki Ota, Soichiro Suzuki, Takuya Moriya, Mitsuru Shiota. Stage IA endometrial cancer recurrence around the ureter after laparoscopic surgery[J]. European Journal of Gynaecological Oncology, 2021, 42(2): 360-364.
No Suggested Reading articles found!