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European Journal of Gynaecological Oncology  2019, Vol. 40 Issue (1): 166-169    DOI: 10.12892/ejgo4629.2019
Case Report Previous articles | Next articles
Ovarian clear cell carcinoma associated with endometriosis: a case report and literature review
M. Terzic1, 2, *(), S. Terzic1, J. Dotlic3, 4, M. Dokic3, 4, M. Mitrovic3, 4, G. Bapayeva2, N. Arsenovic5, A.S. Lagana6, M. Norton4
1Department of Medicine, Nazarbayev University School of Medicine, Astana, Kazakhstan
2Department of Gynecology, National Research Center of Mother and Child Health, University Medical Center, Astana, Kazakhstan
3Clinic of Obstetrics and Gynecology, Clinical Centre of Serbia, Belgrade, Serbia
4Medical Faculty, University of Belgrade, Belgrade, Serbia
5Department of Cellular Pathology, PathLinks Pathology Services, Lincoln County Hospital, Lincoln, United Kingdom
6Department of Obstetrics and Gynecology “Filippo Del Ponte” Hospital, University of Insubria, Varese, Italy
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Abstract  

Purpose: The purpose of this report was to confirm that endometriosis, although a benign gynecological disease, in some patients, can give rise to ovarian cancers. Case Report: The authors report a case of clear cell carcinoma in a patient suffering of endometriosis. The patient, a 38-year old nullipara, had a history of bilateral ovarian cysts diagnosed on routine check-up by ultrasound scan four years ago. After admission to hospital, due to cramping lower abdominal pain, MRI showed tumorous mass, with solid and cystic components, located between abdominal wall, lateral pelvic walls, and lumbosacral part of spine belonging to ovaries. The patient underwent appropriate extensive surgery. Histopathological investigation revealed ovarian clear cell adenocarcinoma Stage IIIa, along with endometriotic cyst found on the contralateral side. Conclusion: This report confirms the strong link between endometriosis and ovarian cancer and sends an appeal for urgent and precise definition of parameters relevant for determination of patients’ groups with the risk for malignancy.

Key words:  Clear cell carcinoma      Endometriosis      Ovarian tumor     
Published:  10 February 2019     
*Corresponding Author(s):  M. TERZIC     E-mail:  terzicmilan@yahoo.co.uk

Cite this article: 

M. Terzic, S. Terzic, J. Dotlic, M. Dokic, M. Mitrovic, G. Bapayeva, N. Arsenovic, A.S. Lagana, M. Norton. Ovarian clear cell carcinoma associated with endometriosis: a case report and literature review. European Journal of Gynaecological Oncology, 2019, 40(1): 166-169.

URL: 

https://ejgo.imrpress.com/EN/10.12892/ejgo4629.2019     OR     https://ejgo.imrpress.com/EN/Y2019/V40/I1/166

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