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European Journal of Gynaecological Oncology  2019, Vol. 40 Issue (6): 1060-1063    DOI: 10.12892/ejgo4661.2019
Case Report Previous articles | Next articles
CD34-positive uterine lipoleiomyoma in a postmenopausal woman with chronic glomerulonephritis
N. Okabe1, M. Fujiwara1, *(), M. Mochizuki2, K. Ohtsuka3, Y. Nishigaya4, Y. Kobayashi4, H. Kamma1
1Department of Pathology, Kyorin University School of Medicine, Shinkawa, Mitaka, Tokyo, Japan
2Department of Clinical Laboratory Science, Teikyo University Faculty of Medical Technology, Itabashi, Tokyo, Japan
3Department of Laboratory Medicine, Kyorin University School of Medicine, Shinkawa, Mitaka, Tokyo, Japan
4Department of Gynecology, Kyorin University School of Medicine, Shinkawa, Mitaka, Tokyo, Japan
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Abstract  

Lipoleiomyomas are rare benign mesenchymal tumors in the uterus that are composed of an admixture of smooth muscle and adipose tissue. Their pathogenesis is still controversial, although many theories have been proposed so far. Herein, the authors report the first case of a CD-34 positive lipoleiomyoma in a patient with chronic glomerulonephritis. A 60-year-old postmenopausal woman with chronic glomerulonephritis and hyperlipidemia underwent a screening ultrasonographic examination, and a mass located on the left side of the uterus was detected. She underwent hysterectomy and bilateral salpingo-oophorectomy. Pathologically, the tumor was composed of an admixture of smooth muscle cells and mature adipocytes. The diagnosis of lipoleiomyoma was made. Immunohistochemically, some smooth muscle cells in the tumor were positive for CD34, which is one of the mesenchymal stem cell markers. The significance of CD34 positivity remains obscure. Further studies are needed to clarify the role of CD34-positive cells in the pathogenesis of lipoleiomyomas.

Key words:  CD34      Chronic glomerulonephritis      Lipoleiomyoma      Uterus     
Published:  10 December 2019     
*Corresponding Author(s):  M. FUJIWARA     E-mail:  masachi@ks.kyorin-u.ac.jp

Cite this article: 

N. Okabe, M. Fujiwara, M. Mochizuki, K. Ohtsuka, Y. Nishigaya, Y. Kobayashi, H. Kamma. CD34-positive uterine lipoleiomyoma in a postmenopausal woman with chronic glomerulonephritis. European Journal of Gynaecological Oncology, 2019, 40(6): 1060-1063.

URL: 

https://ejgo.imrpress.com/EN/10.12892/ejgo4661.2019     OR     https://ejgo.imrpress.com/EN/Y2019/V40/I6/1060

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