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European Journal of Gynaecological Oncology  2020, Vol. 41 Issue (1): 142-144    DOI: 10.31083/j.ejgo.2020.01.4813
Case Report Previous articles | Next articles
Secondary small cell carcinoma of the endometrium after concurrent chemoradiotherapy for cervical cancer: a rare case
R. Tasaka1, Y. Hashiguchi1, *(), M. Kasai1, T. Fukuda1, T. Ichimura1, T. Yasui1, T. Sumi1
1 Department of Obstetrics and Gynecology, Osaka City University Graduate School of Medicine, Osaka, Japan
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Abstract  
Background: Small cell carcinoma of the endometrium is extremely rare. There is no reported case of secondary small cell carcinoma of the endometrium after concurrent chemoradiotherapy for cervical cancer. Case Report: A 48-year-old woman was diagnosed with squamous cell carcinoma of the cervix Stage IIIB (T3bN0M0) and treated by concurrent chemoradiotherapy. After five years and nine months' post-treatment, the woman was diagnosed with small cell carcinoma of the endometrium Stage IIIA (pT3aNXM0). Although the patient received chemotherapy combining paclitaxel and carboplatin postoperatively, she developed a recurrence with pelvic tumor three months after operation. After recurrence, she received one course of chemotherapy combining cisplatin and irinotecan. Although a remarkable reduction of recurrent tumor was found as autopsy findings, she died of disease two months after this chemotherapy. Conclusion: In case of small cell carcinoma of the endometrium, chemotherapy regimen used for small cell lung cancer such as chemotherapy combining cisplatin and irinotecan should be considered.
Key words:  Secondary small cell carcinoma of the endometrium      Concurrent chemoradiotherapy      Cervical cancer     
Published:  15 February 2020     
*Corresponding Author(s):  Y. HASHIGUCHI     E-mail:  hashiguchi@med.osaka-cu.ac.jp

Cite this article: 

R. Tasaka, Y. Hashiguchi, M. Kasai, T. Fukuda, T. Ichimura, T. Yasui, T. Sumi. Secondary small cell carcinoma of the endometrium after concurrent chemoradiotherapy for cervical cancer: a rare case. European Journal of Gynaecological Oncology, 2020, 41(1): 142-144.

URL: 

https://ejgo.imrpress.com/EN/10.31083/j.ejgo.2020.01.4813     OR     https://ejgo.imrpress.com/EN/Y2020/V41/I1/142

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