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European Journal of Gynaecological Oncology  2020, Vol. 41 Issue (4): 651-653    DOI: 10.31083/j.ejgo.2020.04.5182
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Placental site trophoblastic tumor as a rare cause of irregular bleeding in a female of reproductive age
Anastasia Vatopoulou1, *(), Anastasios Liberis2, Alexis Papanikolaou2, Konstantinos Dinas2
1First Department of Obstetrics and Gynecology, Medical School, Aristotle University Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece
2Second Department of Obstetrics and Gynecology, Medical School, Aristotle University Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
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Abstract  
Objective: A case of placental site trophoblastic tumor (PSTT) that presented with abnormal vaginal bleeding is reported because of its rarity. Case report: The patient presented with 8 weeks of amenorrhea, vaginal bleeding and a persistently low titer of β-human chorionic gonadotropin (βhCG). A large circumscribed mass in the uterus was revealed by ultrasound and magnetic resonance imaging. Hysteroscopic biopsy confirmed the presence of PSTT and a hysterectomy was subsequently performed. The patient is well after 6 months of follow up and her βhCG titer normalized. Conclusion: Rare forms of trophoblastic disease should be considered in the differential diagnosis of persistent bleeding and low titers of βhCG.
Key words:  Placental site trophoblastic tumor      Gestational trophoblastic disease      Trophoblastic tumor      Intermediate trophoblasts     
Submitted:  13 March 2018      Accepted:  14 May 2019      Published:  15 August 2020     
*Corresponding Author(s):  ANASTASIA VATOPOULOU     E-mail:  anastvatopoulou@gmail.com

Cite this article: 

Anastasia Vatopoulou, Anastasios Liberis, Alexis Papanikolaou, Konstantinos Dinas. Placental site trophoblastic tumor as a rare cause of irregular bleeding in a female of reproductive age. European Journal of Gynaecological Oncology, 2020, 41(4): 651-653.

URL: 

https://ejgo.imrpress.com/EN/10.31083/j.ejgo.2020.04.5182     OR     https://ejgo.imrpress.com/EN/Y2020/V41/I4/651

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