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European Journal of Gynaecological Oncology  2020, Vol. 41 Issue (4): 536-540    DOI: 10.31083/j.ejgo.2020.04.5294
Original Research Previous articles | Next articles
Prognostic significance of the number of metastatic lymph nodes in early cervical cancer: a retrospective study
Sun Yi Choe1, Jung-Woo Park1, *()
1Department of Obstetrics and Gynecology, Dong-A University College of Medicine, Busan Republic of Korea
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Abstract  
Purpose of Investigation: To determine the significance of positive pelvic lymph node (PLN) metastasis for progression-free survival (PFS) and overall survival (OS) of patients with early cervical cancer alone and in combination with known poor prognostic factors. Materials and Methods: This study was a retrospective analysis of 245 patients with Stage 1A-IIA cervical cancer with radical hysterectomy from 1998-2014. Age, FIGO (International Federation of Gyneacology and Obstetrics) Stage, histologic type, tumor size, stromal invasion depth, PLN metastasis, metastatic PLN numbers, lymphovascular space invasion (LVSI), parametrial invasion, and vaginal resection margin status were collected. PFS and OS were evaluated in accordance with each parameter. Results: Tumor size, LVSI, and metastatic PLN numbers were independently associated with PFS. The metastatic PLN number was associated with both PFS and OS and was an important factor for poor prognosis. Conclusion: These findings may contribute to PFS and OS assessment and treatment modality decisions.
Key words:  Uterine cervical neoplasms      Prognosis      Radical hysterectomy      Metastatic lymph nodes      Lymph node status     
Submitted:  20 June 2019      Accepted:  19 September 2019      Published:  15 August 2020     
Fund: 
Dong-A University research fund
*Corresponding Author(s):  JUNG-WOO PARK     E-mail:  obgypjw@dau.ac.kr

Cite this article: 

Sun Yi Choe, Jung-Woo Park. Prognostic significance of the number of metastatic lymph nodes in early cervical cancer: a retrospective study. European Journal of Gynaecological Oncology, 2020, 41(4): 536-540.

URL: 

https://ejgo.imrpress.com/EN/10.31083/j.ejgo.2020.04.5294     OR     https://ejgo.imrpress.com/EN/Y2020/V41/I4/536

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