Please wait a minute...
European Journal of Gynaecological Oncology  2020, Vol. 41 Issue (4): 531-535    DOI: 10.31083/j.ejgo.2020.04.5351
Original Research Previous articles | Next articles
The effect of age on prediction of concurrent endometrial cancer in patients with atypical endometrial hyperplasia
Yusuf Cakmak1, *(), Tufan Oge1
1Department of Obstetrics and Gynecology, Eskisehir Osmangazi University School of Medicine, 26100. Eskisehir, Turkey
Download:  PDF(314KB)  ( 295 ) Full text   ( 14 )
Export:  BibTeX | EndNote (RIS)      
Abstract  
Purpose: To evaluate the effect of age on prediction of concurrent endometrial cancer (EC) in patients with atypical endometrial hyperplasia (AEH). Materials and Methods: Medical data of 176 patients who were diagnosed with atypical endometrial hyperplasia and underwent surgical treatment enrolled the study group. Clinicopathological features, preoperative and postoperative information were collected. The age distrubition for patients with atypical endometrial hyperplasia and endometrial cancer were examined and stratified according to five-year age increments. Results: Concurrent endometrial cancer was detected in 35(19.8%) patients. atypical endometrial hyperplasia and lower grade hyperplasia (simple or complex) was found in 82(46.5%) and 27(15.3%) patients, respectively. Endometrial cancer was most frequently seen in 51-60 age group. Endometrial cancer in final pathology significantly increased (p = 0,0005) after the age of 53 with sensitivity of 65.52% and 76.67%. Conclusion: Endometrial cancer increases significantly after the age of 53 in patients with atypical endometrial hyperplasia. Based on this study it is recommended that clinicians shoud be aware of this knowledge while informing patients and planning treatment.
Key words:  Age      Atypical endometrial hyperplasia (AEH)      Endometrial cancer (EC)     
Submitted:  21 August 2019      Accepted:  31 October 2019      Published:  15 August 2020     
*Corresponding Author(s):  YUSUF CAKMAK     E-mail:  dryusuf21@gmail.com

Cite this article: 

Yusuf Cakmak, Tufan Oge. The effect of age on prediction of concurrent endometrial cancer in patients with atypical endometrial hyperplasia. European Journal of Gynaecological Oncology, 2020, 41(4): 531-535.

URL: 

https://ejgo.imrpress.com/EN/10.31083/j.ejgo.2020.04.5351     OR     https://ejgo.imrpress.com/EN/Y2020/V41/I4/531

[1] Sigit Purbadi, Gregorius Tanamas, Lisa Novianti. Advanced stage ovarian cancer survival in Jakarta[J]. European Journal of Gynaecological Oncology, 2020, 41(4): 587-590.
[2] Fengyi Xiao, Long Sui. Low-Grade Squamous Intraepithelial Lesion Diagnosed by Colposcopy-Directed Biopsy with More Severe Lesions Undetected[J]. European Journal of Gynaecological Oncology, 2020, 41(4): 617-621.
[3] U Chul Ju, Woo Dae Kang, Seok Mo Kim. Fatal hemorrhage from rupture of metastatic tumors rapidly developed after optimal primary surgery for ovarian angiosarcoma arising from a mature cystic teratoma[J]. European Journal of Gynaecological Oncology, 2020, 41(4): 640-643.
[4] H. Cokmez, A. Yilmaz. Concordance of preoperative and postoperative histological grades in endometrioid type endometrial cancer[J]. European Journal of Gynaecological Oncology, 2020, 41(2): 208-213.
[5] M. Pakiž, A. Dovnik, B. Crnobrnja, P. Zola. Increased incidence of advanced stage endometrial cancer: a retrospective analysis of different clinical approaches and tumour biology[J]. European Journal of Gynaecological Oncology, 2020, 41(2): 246-251.
[6] G. Raba, M. Wieliczko, E. KRASNIANIN. Uterine curettage prior to supracervical hysterectomy identifies a placental trophoblastic tumor – a case study[J]. European Journal of Gynaecological Oncology, 2020, 41(2): 296-298.
[7] X.Z. Cheng, Z. Zhou, M.Y. Yang, Y.L. Cai, F. Deng, X.X. Chen. Prognostic factors for types I and II epithelial ovarian cancer in the elderly[J]. European Journal of Gynaecological Oncology, 2020, 41(1): 7-15.
[8] Y. S. Lee, J. M. Baek, E. K. Park, C. J. Kim, H. J. Lee, J. O. Kim. Expression and therapeutic potential of macrophage migration inhibitory factor and CD74 in ovarian cancer[J]. European Journal of Gynaecological Oncology, 2020, 41(1): 65-69.
[9] K. Madsen, C. Høgdall, A. K. Berthelsen, A. Loft, H. Roed. Diagnostic PET/CT for detecting malignant lymph nodes in patients with cervical cancer Stage IB1[J]. European Journal of Gynaecological Oncology, 2019, 40(6): 953-957.
[10] S.H. Nam, H.R. Yang, D. Kang, K.O. Jung, W.Y. Kim. Survival of advanced epithelial ovarian/fallopian tube/primary peritoneum carcinoma after high-complexity upper abdominal surgery[J]. European Journal of Gynaecological Oncology, 2019, 40(6): 970-976.
[11] K. Suzuki, Y. Ebina, H. Yamada. A case of uncontrollable hemorrhage caused by laparoscopic biopsy for large solitary fibrous tumor in the pelvis[J]. European Journal of Gynaecological Oncology, 2019, 40(6): 1031-1034.
[12] L. N. Abaid, N. Zekry, A. Ronaghi, R. C. Kankus, B. H. Goldstein. Primary management of an extremely large, invasive mucinous ovarian adenocarcinoma: a case report[J]. European Journal of Gynaecological Oncology, 2019, 40(6): 1044-1046.
[13] F.V. Carvalho Sousa Esteves, L.A. Gomes de Sousa, R.S. Martins, A.L. Ramos Bezerra de Alencar, L. de Deus Sousa, M.C. Cronemberger Guimarães Serzedo, I. Meneses de Carvalho Coelho, S.C. Vieira. Paget’s disease of the breast after nipple-areola sparing mastectomy: case report[J]. European Journal of Gynaecological Oncology, 2019, 40(6): 1087-1090.
[14] A. Jaishuen, N. Boonkhum, J. Petsuksiri, N. Jareemit, P. Srichaikul, S. Therasakvichya. Outcomes of treatment for Stage III endometrial carcinoma patients[J]. European Journal of Gynaecological Oncology, 2019, 40(5): 803-809.
[15] S. Kabukcuoglu, B. Hayit. Histopathologic features of advanced stage endometrial carcinoma[J]. European Journal of Gynaecological Oncology, 2019, 40(4): 614-618.
No Suggested Reading articles found!