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European Journal of Gynaecological Oncology  2020, Vol. 41 Issue (5): 821-823    DOI: 10.31083/j.ejgo.2020.05.5429
Case Report Previous articles | Next articles
Secondary small cell vaginal cancer after operative therapy for endometrial cancer
Ikuji Shimazaki1, Yasunori Hashiguchi1, *(), Makoto Yamauchi1, Mari Kasai1, Takeshi Fukuda1, Tomoyuki Ichimura1, Tomoyo Yasui1, Toshiyuki Sumi1
1Department of Obstetrics and Gynecology, Osaka City University Graduate School of Medicine, Japan
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Abstract  
Background: Gynecologic neuroendocrine carcinoma is rare. There is no case report of secondary small cell vaginal cancer after operative therapy for endometrial cancer. Case: A 51 year-old patient was treated by operative therapy for endometrial cancer stage IA (pT1aN0M0). After 9 months' post-treatment, the patient visited the hospital with abnormal bleeding, and a necrotic lesion in the left upper third of the posterior vaginal wall was detected near the vaginal cut edge. Biopsy of this tumor revealed neuroendocrine carcinoma, the patient was diagnosed with small cell carcinoma of the vagina stage I (pT1NXM0) by following operative resection. The patient received chemotherapy with irinotecan and cisplatin. After eleven months of follow-up, the patient remains alive without recurrence. Conclusion: In case of small cell vaginal cancer, chemotherapy regimen with irinotecan and cisplatin should be considered as a therapeutic option.
Key words:  Secondary vaginal cancer      Small cell carcinoma      Endometrial cancer     
Submitted:  08 November 2019      Accepted:  06 May 2020      Published:  15 October 2020     
*Corresponding Author(s):  YASUNORI HASHIGUCHI     E-mail:  hashiguchi@med.osaka-cu.ac.jp

Cite this article: 

Ikuji Shimazaki, Yasunori Hashiguchi, Makoto Yamauchi, Mari Kasai, Takeshi Fukuda, Tomoyuki Ichimura, Tomoyo Yasui, Toshiyuki Sumi. Secondary small cell vaginal cancer after operative therapy for endometrial cancer. European Journal of Gynaecological Oncology, 2020, 41(5): 821-823.

URL: 

https://ejgo.imrpress.com/EN/10.31083/j.ejgo.2020.05.5429     OR     https://ejgo.imrpress.com/EN/Y2020/V41/I5/821

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