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European Journal of Gynaecological Oncology  2019, Vol. 40 Issue (5): 875-878    DOI: 10.12892/ejgo4874.2019
Case Report Previous articles | Next articles
Uterine tumor resembling sex cord stromal tumor - a case report with operative, immunohistochemical and imaging correlation
S. Li1, *(), A. St. Germain2, P. Hui3, A. Finkelstein4, A. Vash-Margita5, M. Azodi5
1Department of Radiology, Yale New Haven Health Bridgeport Hospital, Bridgeport, CT, USA
2Department of Obstetrics and Gynecology, Yale New Haven Health Bridgeport Hospital, Bridgeport, CT, USA
3Department of Pathology, Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA
4Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
5Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA
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Abstract  

Uterine tumor resembling sex cord stromal tumor (UTROSCT) is an unusual and very rare group of tumors, with approximately 70 cases reported to date. The tumor was first described in 1976, and has since been characterized using immunochemistry and cytogenetics. A pathologic diagnosis of UTROSCT is made when the tumor shows characteristic histological features and, in addition, positive immunohistochemical staining of markers of sex cord differentiation (calretinin, melan-A, CD56, CD99 or inhibin). Imaging features, however, are non-specific and cannot be used to reliably differentiate this tumor from other uterine masses, such as leiomyomas. UTROSCT appears heterogeneous on ultrasound, and demonstrates hyperenhancement on earlier arterial phase on computed tomography. These tumors appear T1 hypointense or intermediate and T2 intermediate, but more often T2 hyperintense relative to myometrium; it may have slightly more restricted diffusion as a possible differentiating imaging feature. Due to the rare possibility for metastasis, the present authors believe surgical excision is a reasonable course of management.

Key words:  Uterine tumor resembling sex cord stromal tumors (UTROSCT)      Imaging      SIS      Hysteroscopy      CT      Immunohistochemical stain     
Published:  10 October 2019     
*Corresponding Author(s):  S. LI     E-mail:  dr.shuo.li@gmail.com

Cite this article: 

S. Li, A. St. Germain, P. Hui, A. Finkelstein, A. Vash-Margita, M. Azodi. Uterine tumor resembling sex cord stromal tumor - a case report with operative, immunohistochemical and imaging correlation. European Journal of Gynaecological Oncology, 2019, 40(5): 875-878.

URL: 

https://ejgo.imrpress.com/EN/10.12892/ejgo4874.2019     OR     https://ejgo.imrpress.com/EN/Y2019/V40/I5/875

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